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William M Maniscalco Selected Research

Lung Diseases (Lung Disease)

1/2022Neonatal Hyperoxia Activates Activating Transcription Factor 4 to Stimulate Folate Metabolism and Alveolar Epithelial Type 2 Cell Proliferation.
10/2003Induced p21Cip1 in premature baboons with CLD: implications for alveolar hypoplasia.
10/2002Normal remodeling of the oxygen-injured lung requires the cyclin-dependent kinase inhibitor p21(Cip1/WAF1/Sdi1).
4/2002Angiogenic factors and alveolar vasculature: development and alterations by injury in very premature baboons.

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William M Maniscalco Research Topics

Disease

6Hyperoxia
01/2022 - 07/2002
4Lung Diseases (Lung Disease)
01/2022 - 04/2002
3Bronchopulmonary Dysplasia
01/2022 - 07/2002
2Inflammation (Inflammations)
08/2010 - 10/2002
1Respiratory Distress Syndrome (Acute Respiratory Distress Syndrome)
01/2004
1Premature Birth (Birth, Premature)
01/2004
1Respiratory Insufficiency (Respiratory Failure)
01/2004
1Congenital Diaphragmatic Hernias
09/2002
1Wounds and Injuries (Trauma)
07/2002
1Lung Injury
07/2002
1Vascular System Injuries
07/2002

Drug/Important Bio-Agent (IBA)

3Oxygen (Dioxygen)IBA
01/2004 - 10/2002
2Surface-Active Agents (Surfactants)IBA
11/2006 - 01/2004
2Oxidants (Oxidizing Agents)IBA
09/2005 - 10/2002
2Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
09/2005 - 07/2002
2DNA (Deoxyribonucleic Acid)IBA
05/2004 - 10/2002
2Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
07/2002 - 04/2002
1MitogensIBA
01/2022
1Activating Transcription Factor 4IBA
01/2022
1Methylenetetrahydrofolate Dehydrogenase (NADP) (Dehydrogenase, Methylenetetrahydrofolate)IBA
01/2022
1RNA (Ribonucleic Acid)IBA
01/2022
1Serine (L-Serine)FDA Link
01/2022
1Superoxides (Superoxide)IBA
01/2022
1MitoTEMPOIBA
01/2022
1Folic Acid (Vitamin M)FDA LinkGeneric
01/2022
1CarbonIBA
01/2022
1Fibroblast Growth Factor 7FDA Link
01/2022
1InterleukinsIBA
08/2010
1Macrophage Inflammatory Proteins (Macrophage Inflammatory Protein 1)IBA
08/2010
1Proteins (Proteins, Gene)FDA Link
11/2006
1enhanced green fluorescent proteinIBA
11/2006
18-hydroxyguanineIBA
05/2004
1Vitamin A (Retinol)FDA LinkGeneric
01/2004
1GlucocorticoidsIBA
01/2004
1Cyclin-Dependent Kinase Inhibitor p21IBA
10/2002
1ChemokinesIBA
07/2002

Therapy/Procedure

3Artificial Respiration (Mechanical Ventilation)
08/2010 - 07/2002
1Transcutaneous Electric Nerve Stimulation (TENS)
08/2006
1Therapeutics
01/2004
1Extracorporeal Membrane Oxygenation
09/2002